Stability study of sodium iodide (123 I) oral solution

Authors

  • Erica Araujo Lima Andrade a:1:{s:5:"pt_BR";s:31:"Instituto de Engenharia Nuclear";}
  • Erica Lima
  • Marcilene Carmo
  • Cíntia Custódio Instituto de Engenharia Nuclear
  • Cláudio Reis Sant'anna
  • Rosilene Fiuza
  • Gonçalo Rodrigues
  • Luiz Aleixo
  • Julio Suita

Abstract

Sodium iodide (123 I) produced by the Nuclear Engineering Institute (IEN) is an oral  radiopharmaceutical with a half-life of 13.2 h. It is stored at room temperature (15 - 30 ° C) and its activity is calibrated for the hospital to use the next day. The objective of this work was to evaluate the stability following ANVISA recommendations and determine your shelf life. It is concluded that all criteria for acceptance of quality requirements were met in the period of 48 h.

Linha principal do CV-28: lente quadripolar e distribuidor magnético

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Published

2021-08-12

How to Cite

Andrade, E. A. L. ., Andrade, E. de A. L., Carmo, M. A. S., A. Custódio , C. ., Sant’anna, C. R., Silva, R. F., … Suita, J. C. (2021). Stability study of sodium iodide (123 I) oral solution . Instituto De Engenharia Nuclear: Progress Report, (4). Retrieved from https://revistas.ien.gov.br/index.php/ienprogressreport/article/view/552

Issue

No. 4 (2021): IEN - Progress Report 2018-2020 n.4

Section

Radiopharmaceuticals Production

License

Copyright (c) 2021 Tanira Giara Mello, Erica de Araujo Lima Andrade, Marcilene Aparecida Silva Carmo, Cintia A. Custódio , Cláudio Reis Sant'anna, Rosilene Fiuza Silva, Gonçalo Rodrigues Santos, Luiz Cláudio Martins Aleixo, Julio Cezar Suita

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.